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Although promising, these results warrant further research
Complementing these effects, KPV exerts tissue-selective anti-inflammatory activity by inhibiting NF-B signaling, reducing adhesion molecule expression, and suppressing pro-inflammatory cytokines, thereby maintaining a controlled immune environment conducive to repair
This leads to peripheral and hepatic insulin resistance and compensatory intra-portal hyperinsulinemia, which results in increased hepatic GH sensitivity that aggravates the condition further ( Table 1
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